Alexander Blessin has made three changes from the heavy defeat in Leverkusen as Hauke Wahl, Eric Smith and Joel Chima Fujita come in for Adam Dźwigała, James Sands and Mathias Rasmussen.
Daniel Thioune makes one change from the defeat to Bayern as Samuel Mbangula replaces Karim Coulibaly.
Confirmed St. Pauli vs. Werder Bremen lineups
St. Pauli (3-4-2-1): Vasilj (GK) - Andō, Wahl, Mets - Saliakas, Irvine, Smith, Pyrka - Chima Fujita, Sinani - Kaars
Werder Bremen (3-4-2-1): Backhaus (GK) - Friedl, Stark, Lynen - Njinmah, Puertas, Stage, Agu - Schmid, Mbangula - Grüll