The Boilermakers produced their highest point total in the series since 1999 and their largest victory margin since 1969. Fletcher Loyer and Omer Mayer each added 18 points for Purdue (22-5, 12-4 Big Ten), which took control early with an 11-4 spurt and led wire to wire.
Lamar Wilkerson scored 18 of his 20 points in the second half for Indiana (17-10, 9-7), whose offense never found rhythm. The victory came three days after Purdue lost to top-ranked Michigan.